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Y., Johnson, R

2 Ferroptosis overview In 2003, Dolma and colleagues identified a novel compound, Erastin, through synthetic lethality screening designed to discover anticancer agents

Indeed, measurements of noradrenaline (NA)-induced aerobic glycolysis by FRET nanosensors in individual astrocytes demonstrated an increased glucose utilisation, manifested as reduced NA-elevated free cytosolic glucose concentration, whereas the production of lactate by NA was unaltered

The mitigated effect of NaHS and MG on growth inhibition may be due to the less accumulation of Cd in the aboveground and its translocation from the root to shoot [29], evidenced as the significant reduction of Cd concentrations in the root and leaf compared with Cd treatment alone (Table 2)